NCUIH Sends Letter to HRSA Seeking Exemption for UIOs and Indian Health Care Providers from the 340B Rebate Model Pilot Program

On December 8, 2025, the National Council of Urban Indian Health (NCUIH) sent a letter to the Health Resources and Services Administration (HRSA) Administrator, Thomas J. Engels, to request an exemption for Urban Indian Organizations (UIOs) and Indian Health Care Providers from HRSA’s 340B Rebate Model Pilot Program. NCUIH made this urgent request to prevent the administrative and financial burden of the Program on UIOs and Indian Health Care Providers. This request is consistent with a Tribal request that has been made by both U.S. Department of Health and Human Services’ (HHS) Secretary’s Tribal Advisory Committee (STAC) and the Centers for Medicaid and Medicare Services (CMS) Tribal Technical Advisory Group (TTAG).

Read the full letter here.

Background on the 340B Rebate Model Pilot Program

On July 31, 2025, HRSA announced the voluntary 340B Rebate Model Pilot Program for drugs on the Centers for Medicare and Medicaid Services’ (CMS) Medicare Drug Price Negotiation Selected Drug List for year 2026 from qualifying manufacturers meeting specific criteria. Under the Program, covered entities continue to make purchases through their 340B wholesaler account and request rebates on select drugs after the purchase is made. Read here for more information on the Program.